APO-go^®

Time to switch their OFF’s to ON

Composition
APO-go Pre-filled Syringe (PFS): Apomorphine HCl 5 mg / ml, 10ml (50mg)
APO-go Ampule: Apomorphine HCl 10 mg / ml, 5ml (50mg) and 2ml (20mg)
APO-go Pen: Apomorphine 10mg / ml., 3ml
Excipients: Sodium metabisulfite (E223); Hydrochloric acid (37%) or Sodium Hydroxide and Water for injection

Indication
Indicated for the treatment of disabling motor fluctuations (“on”-“off” phenomena) in patients with Parkinson’s disease which persist despite individually titrated treatment with levodopa and/or other dopamine agonists.

 

Product highlights

• Rapid onset of action (4-12 minutes)

• Rapidly reverses disabling “off” periods

• Quick acting

• Once dose is established, the dose usually does not need to be changed

• There is no significant “dose tolerance to the effect of Apomorphine”

• Reduce formalized care

• Improves activities of daily living and promotes independence of patient

• Can be used as an adjunct therapy to give greater patient control of debilitating “off”   episodes (APO-go Pen)

• Takes control of the symptoms and manages “off” episodes effectively
   ° 64% daily “off” time reduction from baseline in monotherapy and 18% in polytherapy       groups

 

   ° Reduces dyskinesia severity from baseline, 64% in monotherapy group and 30% in
      polytherapy group

   ° Dyskinesia severity and duration significantly less in monotherapy vs. polytherapy group

 

 

Availability/dosage form

 

APO-go ampule 10mg/mL, 5mL (50mg) and 2mL (20mg)

APO-go Pre-filled Syringe (PFS) 5mg/ml, 10mL (50mg)

 

APO-go Pen 10mg/mL, 3mL (30mg)

 

Crono APO-go Ambulatory Infusion Pump

 

 

APO-go ampule and APO-go Pre-Filled Syringe (PFS) are for continuous subcutaneous infusion with APO-go Crono Pump